abstract：:Calcium polyphosphate is a biodegradable bone substitute. It remains a challenge to prepare porous calcium polyphosphate with desired gradient porous structures. In this study, a modified one-step gravity sintering method was used to prepare calcium polyphosphate scaffolds with desired-gradient-pore-size distribution....

journal_title：Journal of biomaterials applications

authors： Chen L,Song W,Markel DC,Shi T,Muzik O,Matthew H,Ren W

更新日期：2016-02-01 00:00:00

abstract：:In this work, we report brushite-based calcium phosphate cement (CPC) system to enhance the in vivo biodegradation and tissue in-growth by incorporation of micro-channeled hydroxyapatite (HAp) granule and silicon and sodium addition in calcium phosphate precursor powder. Sodium- and silicon-rich calcium phosphate powd...

journal_title：Journal of biomaterials applications

authors： Sarkar SK,Lee BY,Padalhin AR,Sarker A,Carpena N,Kim B,Paul K,Choi HJ,Bae SH,Lee BT

更新日期：2016-01-01 00:00:00

abstract：:The aim of the paper is to obtain and characterize k-carrageenan-chitosan dual hydrogel multilayers shell BSA gel microcapsules, as a carrier for curcumin, and as a possible antitumoral agent in biological studies. We used the CaCO3 template to synthesize non-toxic CaCO3/BSA particles as microtemplates by coprecipitat...

journal_title：Journal of biomaterials applications

authors： Paşcalău V,Soritau O,Popa F,Pavel C,Coman V,Perhaita I,Borodi G,Dirzu N,Tabaran F,Popa C

更新日期：2016-01-01 00:00:00

abstract：:Nowadays, exceptional advantages of silk fibroin over synthetic and natural polymers have impelled the scientists to application of this biomaterial for tissue engineering purposes. Recently, we showed that embedding natural degummed silk fibers in regenerated Bombyx mori silk-based scaffold significantly increases th...

journal_title：Journal of biomaterials applications

authors： Mobini S,Taghizadeh-Jahed M,Khanmohammadi M,Moshiri A,Naderi MM,Heidari-Vala H,Ashrafi Helan J,Khanjani S,Springer A,Akhondi MM,Kazemnejad S

更新日期：2016-01-01 00:00:00

abstract：:Hydroxyapatite (Ca10(PO4)6(OH)2) is widely investigated as an implantable material for hard tissue restoration due to its osteoconductive properties. However, hydroxyapatite in bulk form is limited as its mechanical properties are insufficient for load-bearing orthopedic applications. Attempts have been made to improv...

journal_title：Journal of biomaterials applications

authors： Yatongchai C,Placek LM,Curran DJ,Towler MR,Wren AW

更新日期：2015-11-01 00:00:00

abstract：:Engineered anisotropic tissue constructs containing aligned cell and extracellular matrix structures are useful as in vitro models and for regenerative medicine. They are of particular interest for nervous system modelling and regeneration, where tracts of aligned neurons and glia are required. The self-alignment of c...

journal_title：Journal of biomaterials applications

authors： O'Rourke C,Drake RA,Cameron GW,Loughlin AJ,Phillips JB

更新日期：2015-11-01 00:00:00

abstract：:Gold nanomaterials possess unique physical and chemical properties, which attracted much attention in recent years. As a new type of gold nanomaterials, gold nanostars (GNSTs) have been prepared and characterized in this study. GNSTs under near-infrared (NIR) light irradiation can exert not only cancer photothermal th...

journal_title：Journal of biomaterials applications

authors： Wang L,Meng D,Hao Y,Zhao Y,Li D,Zhang B,Zhang Y,Zhang Z

更新日期：2015-11-01 00:00:00

abstract：:Chitosan-glutaraldehyde microparticles were produced by emulsion crosslinking method to be used as drug delivery system for polyphenols from Thymus serpyllum L. aqueous extract. The effect of preparation conditions, chitosan concentration (1.5-3% w/v), and glutaraldehyde/chitosan (GA/Ch) mass ratio (0.15-1.20) on wate...

journal_title：Journal of biomaterials applications

authors： Trifković K,Milašinović N,Djordjević V,Zdunić G,Kalagasidis Krušić M,Knežević-Jugović Z,Šavikin K,Nedović V,Bugarski B

更新日期：2015-11-01 00:00:00

abstract：:Even though Ti-based implants are the most used materials for hard tissue replacement, they may present lack of osseointegration on the long term, due to their inertness. Hydrothermal treatment (HT) is a useful technique for the synthesis of firmly attached, highly crystalline coatings made of anatase titanium dioxide...

journal_title：Journal of biomaterials applications

authors： Lorenzetti M,Dakischew O,Trinkaus K,Lips KS,Schnettler R,Kobe S,Novak S

更新日期：2015-07-01 00:00:00

abstract：:Aluminum-free glass ionomer cements (GICs) are under development for orthopedic applications, but are limited by their insufficient handling properties. Here, the addition of calcium polyphosphate (CPP) was investigated as an additive to an experimental zinc-silicate glass ionomer cement. A 50% maximum increase in wor...

journal_title：Journal of biomaterials applications

authors： Valliant EM,Gagnier D,Dickey BT,Boyd D,Filiaggi MJ

更新日期：2015-07-01 00:00:00

abstract：:The animal immune response against Galα1,3-Galβ1-4GlcNAc-R(α-Gal) epitopes gives an important cause for the failure of glutaraldehyde(GA)-fixed cardiac xenografts. This study aimed to assess the in vivo effect of our novel combined anticalcification treatment, which includes immunologic modification, using α1,3-galact...

journal_title：Journal of biomaterials applications

authors： Lim HG,Choi SY,Jeong S,Shin JS,Park CG,Kim YJ

更新日期：2015-02-01 00:00:00

abstract：:The process of molecular self-assembly plays a crucial role in formulation of polymeric nanoparticulated drug delivery carriers as it creates the possibility for enhanced drug encapsulation and carrier surface engineering. This study aimed to develop a novel self-assembled polymeric micelles for targeted delivery in t...

journal_title：Journal of biomaterials applications

authors： Djurdjic B,Dimchevska S,Geskovski N,Petrusevska M,Gancheva V,Georgiev G,Petrov P,Goracinova K

更新日期：2015-01-01 00:00:00

abstract：:Three types of commercially available ultra-high molecular weight polyethylene (UHMWPE) acetabular cups currently used in total hip arthroplasty have been studied by means of Raman micro-spectroscopy to unfold the microstructural modification induced by the oxidative degradation after accelerated aging with and withou...

journal_title：Journal of biomaterials applications

authors： Puppulin L,Zhu W,Sugano N,Pezzotti G

更新日期：2015-01-01 00:00:00

abstract：:Bone tissue is dependent on an efficient blood supply to ensure delivery of nutrients and oxygen. One method to acquire a vascular-engineered bone tissue could be the use of an angiogenic gene-activated scaffold. In the current study, porous chitosan/hydroxyapatite (C/HA) scaffolds were fabricated via freeze-drying wi...

journal_title：Journal of biomaterials applications

authors： Koç A,Finkenzeller G,Elçin AE,Stark GB,Elçin YM

更新日期：2014-11-01 00:00:00

abstract：:In this work, the role of shock wave-induced increase of bone morphogenetic proteins in modulating the osteogenic properties of osteoblast-like cells seeded on a bioactive scaffold was investigated using gremlin as a bone morphogenetic protein antagonist. Bone-like glass-ceramic scaffolds, based on a silicate experime...

journal_title：Journal of biomaterials applications

authors： Muzio G,Martinasso G,Baino F,Frairia R,Vitale-Brovarone C,Canuto RA

更新日期：2014-11-01 00:00:00

abstract：:Calcium phosphate fillers have been shown to increase cement osteoconductivity, but have caused drawbacks in cement properties. Hydroxyapatite and Brushite were introduced in an acrylic two-solution cement at varying concentrations. Novel composite bone cements were developed and characterized using rheology, injectab...

journal_title：Journal of biomaterials applications

authors： Aghyarian S,Rodriguez LC,Chari J,Bentley E,Kosmopoulos V,Lieberman IH,Rodrigues DC

更新日期：2014-11-01 00:00:00

abstract：:An experimental and computational investigation of the self-tapping ability of carbon fibre reinforced polyetheretherketone (CFR-PEEK) has been conducted. Six CFR-PEEK suture anchor designs were investigated using PEEK-OPTIMA® Reinforced, a medical grade of CFR-PEEK. Experimental tests were conducted to investigate th...

journal_title：Journal of biomaterials applications

authors： Feerick EM,Wilson J,Jarman-Smith M,Ó'Brádaigh CM,McGarry JP

更新日期：2014-10-01 00:00:00

abstract：:Hemocompatibility is the goal for any biomaterial contained in extracorporeal life supporting medical devices. The hallmarks for hemocompatibility include nonthrombogenicity, platelet preservation, and maintained platelet function. Both in vitro and in vivo assays testing for compatibility of the blood/biomaterial int...

journal_title：Journal of biomaterials applications

authors： Major TC,Handa H,Annich GM,Bartlett RH

更新日期：2014-10-01 00:00:00

abstract：:In this study, a phosphorylation treatment of porous anodic alumina (PAA) was performed by wet impregnation in phosphoric acid and a subsequent heat treatment. The PAA and phosphorylated PAA specimens were analyzed using a field emission scanning electron microscope, an energy-dispersive X-ray spectrometer, and Fourie...

journal_title：Journal of biomaterials applications

authors： Li X,Ni S,Webster TJ

更新日期：2014-09-01 00:00:00

abstract：:The purpose of this research was to develop novel nanoparticles (NPs) of star-like copolymer mannitol-functionalized poly(lactide)-vitamin E TPGS (M-PLA-TPGS) for paclitaxel delivery for prostate cancer treatment, and evaluate their therapeutic effects in prostate cancer cell line and animal model in comparison with t...

journal_title：Journal of biomaterials applications

authors： Wang K,Guo L,Xiong W,Sun L,Zheng Y

更新日期：2014-09-01 00:00:00

abstract：:The aim of this study was to compare the osteogenic effects of periodontal ligament stem cells (PDLSCs) versus bone marrow mesenchymal stem cells (BMMSCs) in combination with Bio-Oss scaffolds on subcutaneous and critical-size defects in the immunodeficient rat calvarium. PDLSCs and BMMSCs were obtained from the same ...

journal_title：Journal of biomaterials applications

authors： Yu BH,Zhou Q,Wang ZL

更新日期：2014-08-01 00:00:00

abstract：:Carbon-fibre-reinforced polyether ether ketone (CFR-PEEK) exhibits excellent biomechanical properties as it has an elastic modulus similar to bone. However, CFR-PEEK displays inferior biocompatibility compared with titanium alloy and coating techniques are therefore of interest in order to improve integration. In this...

journal_title：Journal of biomaterials applications

authors： Suska F,Omar O,Emanuelsson L,Taylor M,Gruner P,Kinbrum A,Hunt D,Hunt T,Taylor A,Palmquist A

更新日期：2014-08-01 00:00:00

abstract：:Bone tissue engineering, which relies on the interactions between stem cells and suitable scaffold materials, represents a highly desirable alternative to currently used allograft or autograft strategies for the treatment of bone defects caused by injury or disease, with one of the major challenges being to generate s...

journal_title：Journal of biomaterials applications

authors： Feng J,Chong M,Chan J,Zhang Z,Teoh SH,Thian ES

更新日期：2014-07-01 00:00:00

abstract：:In the present study, a novel hydrogel-grafted fabrics embedding of berberine nanosuspension was developed for the treatment of infected wound. Hydrogel-grafted fabric was prepared by graft copolymerization of N-isopropylacrylamide and alginate using ceric ammonium nitrate as initiator. Berberine nanosuspension was pr...

journal_title：Journal of biomaterials applications

authors： Xu H,Yuan XD,Shen BD,Han J,Lv QY,Dai L,Lin MG,Yu C,Bai JX,Yuan HL

更新日期：2014-05-01 00:00:00

abstract：:In this paper, the authors describe a novel type of hydrogel coating prepared from the copolymer of human serum albumin and oxidized dextran. The material was designed as a hydrogel sealant for polyester (Dacron®)-based vascular grafts. Dextran was chosen as a coating material due to its anti-thrombogenic properties. ...

journal_title：Journal of biomaterials applications

authors： Lisman A,Butruk B,Wasiak I,Ciach T

更新日期：2014-05-01 00:00:00

abstract：:Nanohydroxyapatite (nanoHA), due to its chemical properties, has appeared as an exceptionally promising bioceramic to be used as bone regeneration material. Staphylococcus epidermidis have emerged as major nosocomial pathogens associated with infections of implanted medical devices. In this work, the purpose was to st...

journal_title：Journal of biomaterials applications

authors： Barros J,Grenho L,Manuel CM,Ferreira C,Melo L,Nunes OC,Monteiro FJ,Ferraz MP

更新日期：2014-05-01 00:00:00

abstract：:The purpose of this study was to develop a specific targeting magnetic nanoparticle probe for magnetic resonance imaging and therapy in the form of local hyperthermia. Carboxymethyl dextran-coated ultrasmall superparamagnetic iron oxide nanoparticles with carboxyl groups were coupled to cyclic arginine-glycine-asparti...

journal_title：Journal of biomaterials applications

authors： Zheng SW,Huang M,Hong RY,Deng SM,Cheng LF,Gao B,Badami D

更新日期：2014-03-01 00:00:00

abstract：:The aim of this study was to design a new natural/synthetic bioactive bone scaffold for potential use in bone replacement applications. We developed a tri-component osteogenic composite scaffold made of collagen (Coll), hydroxyapatite (HA) and poly(l-lactide-co-ε-caprolactone) (PLCL). This Coll/HA/PLCL composite scaff...

journal_title：Journal of biomaterials applications

authors： Akkouch A,Zhang Z,Rouabhia M

更新日期：2014-02-01 00:00:00

abstract：:The present article deals with the development of 3D porous scaffolds for bone grafting. They were prepared based on rapid fluid infiltration of Al2O3-SiO2 sol into a polyethylene non-woven fabric template structure. Titanium dioxide in concentration equal to 5 wt% was added to the Al2O3-SiO2 mixture to produce Al2O3-...

journal_title：Journal of biomaterials applications

authors： Naga SM,El-Kady AM,El-Maghraby HF,Awaad M,Detsch R,Boccaccini AR

更新日期：2014-02-01 00:00:00

abstract：:The setup of colloidal hybrid nanosystems based on biomimetic calcium phosphate apatites doped with europium ions has recently raised great interest in the pharmacological community, especially due to their bio-inspired character. This is especially relevant in relation with medical imaging for cancer diagnosis. Quest...

journal_title：Journal of biomaterials applications

authors： Al-Kattan A,Santran V,Dufour P,Dexpert-Ghys J,Drouet C

更新日期：2014-01-01 00:00:00

abstract：:Biodegradable magnesium-based implants are currently being developed for use in orthopedic applications. The aim of this study was to investigate the acute, subacute, and chronic local effects on bone tissue as well as the systemic reactions to a magnesium-based (MgYREZr-alloy) screw containing rare earth elements. Th...

journal_title：Journal of biomaterials applications

authors： Waizy H,Diekmann J,Weizbauer A,Reifenrath J,Bartsch I,Neubert V,Schavan R,Windhagen H

更新日期：2014-01-01 00:00:00

abstract：:Cellulose acetate phthalate and Pluronic F-127 combined together (70:30 wt:wt) create a rigid, surface-eroding association polymer. To impart flexibility into the polymer system and allow for a drug delivery film that can contour to varying wound shapes, plasticizers were added. Triethyl citrate or tributyl citrate wa...

journal_title：Journal of biomaterials applications

authors： Rabek CL,Van Stelle R,Dziubla TD,Puleo DA

更新日期：2014-01-01 00:00:00

abstract：:The aim of this pilot study was to evaluate the bioactive, surface-coated polycaprolactone-co-lactide scaffolds as bone implants in a tibia critical size defect model. Polycaprolactone-co-lactide scaffolds were coated with collagen type I and chondroitin sulfate and 30 piled up polycaprolactone-co-lactide scaffolds we...

journal_title：Journal of biomaterials applications

authors： Rentsch C,Schneiders W,Hess R,Rentsch B,Bernhardt R,Spekl K,Schneider K,Scharnweber D,Biewener A,Rammelt S

更新日期：2014-01-01 00:00:00

abstract：:Single nanofibers with chemical and functional properties consistent with artery extracellular matrix nanofibers were produced by electrospinning. Using weight ratios to mimic artery extracellular matrix, five materials were tested: (1) Collagen type I, (2) Collagen type I + Collagen type III, (3) Collagen type I + po...

journal_title：Journal of biomaterials applications

authors： Liu J,Argenta L,Morykwas M,Wagner WD

更新日期：2014-01-01 00:00:00

abstract：:Sternotomy and sternal closure occur prior to and post cardiac surgery, respectively. Although post-operative complications associated with poor sternal fixation can result in morbidity, mortality, and considerable resource utilization, sternotomy is preferred over other methods such as lateral thoracotomy. Rigid ster...

journal_title：Journal of biomaterials applications

authors： Alhalawani AM,Towler MR

更新日期：2013-11-01 00:00:00

abstract：:Eight different chemicals were investigated as potential candidate coupling agents for phosphate glass fibre reinforced polylactic acid composites. Evidence of reaction of the coupling agents with phosphate glass and their effect on surface wettability and glass degradation were studied along with their principle role...

journal_title：Journal of biomaterials applications

authors： Hasan MS,Ahmed I,Parsons AJ,Rudd CD,Walker GS,Scotchford CA

更新日期：2013-09-01 00:00:00

abstract：:A range of crystalline and nano-sized carbonate- and silicate-substituted hydroxyapatite has been successfully produced by using continuous hydrothermal flow synthesis technology. Ion-substituted calcium phosphates are better candidates for bone replacement applications (due to improved bioactivity) as compared to pha...

journal_title：Journal of biomaterials applications

authors： Chaudhry AA,Knowles JC,Rehman I,Darr JA

更新日期：2013-09-01 00:00:00

abstract：:Polyelectrolyte capsules are seen as promising nanotechnology based drug delivery systems. In previous works, we have demonstrated the possibility to fabricate bio-activated surface layer containing capsules with improved features in terms of biocompatibility. In this study, we have characterized the permeability prop...

journal_title：Journal of biomaterials applications

authors： Habibi N,Pastorino L,Sandoval OH,Ruggiero C

更新日期：2013-08-01 00:00:00

abstract：:Staphylococcus epidermidis plays a major role in capsular contractures of silicone breast implants. This in vitro study evaluates the antibacterial effect of copper on S. epidermidis in silicone implants. Specimens of a silicone material used for breast augmentation (Cu0) and specimens coated with different copper con...

journal_title：Journal of biomaterials applications

authors： Gosau M,Bürgers R,Vollkommer T,Holzmann T,Prantl L

更新日期：2013-08-01 00:00:00

abstract：:This investigation describes the synthesis and in vitro evaluation of cationic hydrogel sub-microparticles based on polydimethylaminoethylmethacrylate for oral insulin delivery. Polymerization of dimethylaminoethylmethacrylate was carried out in aqueous medium with potassium persulfate as the initiator. Quaternization...

journal_title：Journal of biomaterials applications

authors： Sonia TA,Sharma CP

更新日期：2013-07-01 00:00:00